In 2004, he hit three home runs (twice) in the single game, becoming only the 14th player in MLB history to do so. Also during his stint with the Chicago Cubs, Ramirez hit his 200th career home run and also had one of the best games of his career, ending a crucial game (ironically) against the Milwaukee Brewers with a two-out, two-run home run at the bottom of the ninth inning off of pitcher Francisco Cordero to cap a five-run comeback win. Ramirez was later signed to the Milwaukee Brewers in 2011, where he committed to a three-year agreement. He rebounded from a slow 2012 start by having a solid offensive season and finishing that season with a .300 batting average, with 27 home runs, 105 RBIs as well as a league-leading 50 doubles.