In 2013 Webb starred as Cookie in the television series LearningTown. Since 2010 she has starred as Imunique in the series Love That Girl!. She has also starred as Teresa Morris in Grey’s Anatomy in 2014. Bresha has starred in the films The American Mall, Return to Zero and At the Devil’s Door. She has also appeared on the TV shows Private Practice, Raising the Bar, Hung, In the Flow with Affion Crockett, Bandwagon: The Series, King Bachelor’s Pad, and Weeds. She was featured on a Saturday Night Live special showcase featuring African American female comedians.