He was drafted #38 by the Chicago Bulls in the 2004 NBA Draft. Duhon played for the Bulls from 2004 to 2008 and then signed a two year deal with the New York Knicks for $12 million where he played from 2008 to 2010. He signed a four year deal worth $15 million with the Orlando Magic where he played from 2010 to 2012. He was traded to the Los Angeles Lakers where he finished his career before being waved in 2013. In April 2014 Duhon was hired to be an assistant coach at Marshall University under head coach Dan D’Antoni. Duhon’s cousin is NBA player Jarrett Jack.