Under Ragon guidance, InterSystems has evolved into a thriving company selling the guts of electronic health records: databases that can easily ramp up and allow doctors to quickly retrieve patient information. Along with his wife Susan, an executive at InterSystems, Ragon pledged $100 million over 10 years to establish the Ragon Institute of MGH (Massachusetts General Hospital), MIT and Harvard. It’s an Institute that works on the development of an HIV vaccine.