In 2010 he had a recurring role as Zach in the series United States of Tara. From 2010 to 2013 he starred as Lincoln Lee in the series Fringe. In 2014 Gabel starred as Cotton Mather in the WGN America series Salem. Seth has also starred in the movies The Da Vinci Code, Jonah Hex, and Take Me Home Tonight. He has appeared in episodes of the TV series Law & Order: Special Victims Unit, The Closer, CSI: Crime Scene Investigation, Ironside, and Arrow. Gabel was nominated for a Saturn Award in 2011 for Best Guest Starring Role on Television for Fringe. Seth married actress (and daughter of Ron Howard) Bryce Dallas Howard in 2006 and the couple has two children together.