His best known role came starring as Jake in the series Outnumbered from 2007 to 2014. From 2012 to 2014 Drew-Honey starred as Dylan in the TV series Cuckoo. He starred in the movies Horrid Henry: The Movie in 2011 and Up All Night in 2015. Drew-Honey presented the television series Friday Download from 2011 to 2012. He was nominated for a British Comedy Award for Best Male Comedy Newcomer in 2009 for Outnumbered.
